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NEUROSAE 2018 ANNUAL MEETING EDITION (VOLUME 10, ISSUE 3)
QUESTION 55 OF 100
A 28-year-old woman recently diagnosed with systemic lupus erythematosus (SLE) is referred to neurology clinic for some non specific sensory symtoms . She is fearful of having a stroke as her cousin had a stroke at age 55 who also has lupus. The patient is advised about different neuropsychatric symptoms that can be occur SLE. The patient should be informed that the most common neuropsychiatric symptom associated with SLE is which of the following?
B. Mood disorder **
C. Cognitive dysfunction
E. Cerebrovascular disease
** = Your answer
The five most common CNS syndromes (pooled prevalence from prospective studies) appear to be headache (23.3%; 37% when excluding studies underreporting or not including headache), mood disorders (14.9%), cognitive dysfunction (13.9%; 23% to 60% when only including studies using formal neuropsychological testing), seizures (8.0%), and cerebrovascular disease (7.2%). Although stroke is an associated risk, the patient can be counseled that she is more at risk the former symptoms and syndromes.
* Dimberg EL. Rheumatology and neurology. Continuum Lifelong Learning Neurol. 2017;23(3):691-721.