Neurology Editors’ Choice: Top Stories of 2015 los mejores estudios de neurología del 2015


Information sourced from NEJM Journal Watch:

Neurology Editors’ Choice: Top Stories of 2015

  1. Andrew Josephson, MD

A perspective on the most important research in the field from the past year

I am pleased to introduce this year’s NEJM Journal Watch Neurology Top Ten Stories of 2015. As in years past, I have made these selections after carefully reviewing all of the year’s summaries. In making the choices, I have tried to strike a balance between relevance to the clinician, recognition of landmark studies, and media publicity and public awareness. The sequence of stories is not intended to reflect their relative importance. I hope you find the list useful and thought-provoking.

The Neurology Top Stories of 2015, in no particular order, are:

Compelling Evidence That Modern Endovascular Therapy Improves Stroke Outcomes
[Berkhemer OA et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015 Jan 1; 372:11. Full-text NEJM article PDF | PubMed® abstract]

Symptoms of Parkinson Disease a Decade Before Diagnosis
[Schrag A et al. Prediagnostic presentations of Parkinson’s disease in primary care: A case-control study. Lancet Neurol 2015 Jan; 14:57. Full-text Lancet Neurol article PDF | PubMed® abstract]

Barriers to Referral for Epilepsy Surgery Evaluation
[Roberts JI et al. Neurologists’ knowledge of and attitudes toward epilepsy surgery: A national survey. Neurology 2015 Jan 13; 84:159. Full-text Neurology article PDF in PubMed® Central |PubMed® abstract]

Neuropathic Pain Therapy: Evidence-Based Recommendations
[Finnerup NB et al. Pharmacotherapy for neuropathic pain in adults: A systematic review and meta-analysis. Lancet Neurol 2015 Feb; 14:162. PubMed® abstract]

Can Ineffective Acute Migraine Treatment Lead to Chronic Migraine?
[Lipton RB et al. Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine. Neurology 2015 Feb 17; 84:688. PubMed® abstract]

Blood Biomarkers for Amyotrophic Lateral Sclerosis
[Lu C-H et al. Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis. Neurology 2015 Jun 2; 84:2247. Full-text Neurology article PDF in PubMed® Central | PubMed® abstract]

Is Status Epilepticus Becoming More Frequent?
[Betjemann JP et al. Trends in status epilepticus—related hospitalizations and mortality: Redefined in US practice over time.JAMA Neurol 2015 Jun; 72:650. PubMed® abstract]

Oral vs. Intravenous High-Dose Glucocorticoids for MS Relapses: Your Choice
[Le Page E et al. Oral versus intravenous high-dose methylprednisolone for treatment of relapses in patients with multiple sclerosis (COPOUSEP): A randomised, controlled, double-blind, non-inferiority trial. Lancet 2015 Sep 5; 386:974. PubMed® abstract]

A Clinical Decision Tool for Patients with Cerebral Aneurysms
[Etminan N et al. The unruptured intracranial aneurysm treatment score: A multidisciplinary consensus. Neurology 2015 Sep 8; 85:881. Full-text Neurology article PDF in PubMed® Central |PubMed® abstract]

Is Multiple System Atrophy a Prion Disorder?
[Prusiner SB et al. Evidence for α-synuclein prions causing multiple system atrophy in humans with Parkinsonism. Proc Natl Acad Sci U S A 2015 Sep 22; 112:E5308. PubMed® abstract]

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