Medicine Year in Review 2012

Information sourced from Journal Watch:

General Medicine Year in Review 2012

The most important medical topics of 2012, as chosen by the editors of Journal Watch General Medicine

Each year, the editors of Journal Watch General Medicine choose the year’s most important thematic areas in clinical research. We try to strike a balance between relevance to primary care, recognition of landmark studies, and media publicity and public awareness. Some of our stories emerge from one important study, and others come from several studies on a single topic. The order of these stories is not intended to reflect their relative importance.

OUR YEAR IN REVIEW TOPICS FOR 2012:

A Cardiovascular Quartet
[Closure or medical therapy for cryptogenic stroke with patent foramen ovale. Furlan AJ et al. N Engl J Med 2012 Mar 15; 366:991. Free full-text article PDF | PubMed ® abstract]
[Strategies for multivessel revascularization in patients with diabetes. Farkouh ME et al. for the FREEDOM Trial Investigators. N Engl J Med 2012 Dec 20;367(25):2375-84. PubMed ® abstract]
[Compelling evidence for coronary-bypass surgery in patients with diabetes. Hlatky MA. N Engl J Med 2012; 367:2437-2438. NEJM Editorial preview]
[Two-year outcomes after transcatheter or surgical aortic-valve replacement. Kodali SK et al. N Engl J Med 2012 May 3; 366:1686. Free full-text article PDF | PubMed ® abstract]
[Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. Makkar RR et al. N Engl J Med 2012 May 3; 366:1696. Free full-text article PDF | PubMed ® abstract]
[Warfarin and aspirin in patients with heart failure and sinus rhythm. Homma S et al. N Engl J Med 2012; 366:1859-1869. Free full-text article PDF | PubMed ® abstract]

When to Repeat Bone-Density Testing Depends on Initial T Score
[Bone-density testing interval and transition to osteoporosis in older women. Gourlay ML et al. N Engl J Med 2012 Jan 19; 366:225. Free full-text article PDF | PubMed ® abstract]

Radical Prostatectomy for Patients with Prostate-Specific Antigen €“Detected Cancer
[Radical prostatectomy versus observation for localized prostate cancer. Wilt TJ et al. N Engl J Med 2012 Jul 19; 367:203. Free full-text manuscript in PubMed ® Central| PubMed ® abstract]

Epidural Corticosteroid Injections for Sciatica
[Epidural steroids, etanercept, or saline in subacute sciatica: A multicenter, randomized trial. Cohen SP et al. Ann Intern Med 2012 Apr 17; 156:551. PubMed ® abstract]
[Epidural corticosteroid injections in the management of sciatica: A systematic review and meta-analysis. Pinto RZ et al. Ann Intern Med 18 December 2012;157(12):865-877. Annals review article abstract]

CT Angiography in the ED €” A Better Test for Patients with Chest Pain?
[CT angiography for safe discharge of patients with possible acute coronary syndromes. Litt HI et al. N Engl J Med 2012; 366:1393-1403. Free full-text article PDF | PubMed ® abstract]
[Coronary CT angiography versus standard evaluation in acute chest pain. Hoffmann U et al. N Engl J Med 2012 Jul 26; 367:299. PubMed ® abstract]
[Coronary CT angiography for acute chest pain. Redberg RF. N Engl J Med 2012 Jul 26; 367:375. NEJM Editorial preview]

Evolving Consensus on Managing Patients with Type 2 Diabetes
[Management of hyperglycemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Inzucchi SE et al. Diabetes Care 2012 Jun; 35:1364. Free full-text article PDF | PubMed ® abstract]
[Long-term effects of intensive glucose lowering on cardiovascular outcomes. The ACCORD Study Group. N Engl J Med 2011 Mar 3; 364:818. Free full-text article PDF | PubMed ® abstract]
[Standards of Medical Care in Diabetes €”2012. Diabetes Care January 2012 vol. 35 no. Supplement 1 S11-S63. Free full-text article PDF | article extract]
[Intensive and standard blood pressure targets in patients with type 2 diabetes mellitus: Systematic review and meta-analysis. McBrien K et al. Arch Intern Med 2012 Sep 24; 172:1296. PubMed ® abstract]
[Meta-analysis of individual patient data in randomised trials of self monitoring of blood glucose in people with non-insulin treated type 2 diabetes. Farmer AJ et al. BMJ 2012 Feb 27; 344:e486. Free full-text article PDF | PubMed ® abstract]
[Health benefits of gastric bypass surgery after 6 years. Adams TD et al. JAMA 2012 Sep 19; 308:1122. PubMed ® abstract]

End-of-life Care in the Intensive Care Unit
[Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians. Piers RD et al. JAMA 2011 Dec 28; 306:2694. Free full-text article PDF | PubMed ® abstract]
[Recommendations to limit life support: A national survey of critical care physicians. Brush DR et al. Am J Respir Crit Care Med 2012 Oct 1; 186:633. PubMed ® abstract]

Most Sinus Complaints Don’t Require Antibiotics
[Prospective observational study of chronic rhinosinusitis: Environmental triggers and antibiotic implications. Ferguson BJ et al. Clin Infect Dis 2012 Jan 1; 54:62. Free full-text article PDF | PubMed ® abstract]
[Amoxicillin for acute rhinosinusitis: A randomized controlled trial. Garbutt JM et al. JAMA 2012 Feb 15; 307:685. Free full-text article PDF | PubMed ® abstract]
[Systemic corticosteroid monotherapy for clinically diagnosed acute rhinosinusitis: a randomized controlled trial. Venekamp RP. CMAJ. 2012 Oct 2;184(14):E751-7. Free full-text article PDF | PubMed ® abstract]
[IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Chow AW et al. Clin Infect Dis 2012 Apr 15; 54:1041. Free full-text article PDF | PubMed ® abstract]

Prophylaxis After Treatment for Unprovoked Venous Thromboembolism
[Aspirin for preventing the recurrence of venous thromboembolism. Becattini C et al. N Engl J Med 2012 May 24; 366:1959. Free full-text article PDF | PubMed ® abstract]
[Low-dose aspirin for preventing recurrent venous thromboembolism. Brighton TA et al. N Engl J Med 2012; 367:1979-1987. PubMed ® abstract]

Thrombosis Prophylaxis for Medical Inpatients: How Do We Weigh Risks and Benefits?
[Low-molecular-weight heparin and mortality in acutely ill medical patients. Kakkar AK et al. N Engl J Med 2011 Dec 29; 365:2463. Free full-text article PDF | PubMed ® abstract]
[Venous thromboembolism prophylaxis in hospitalized patients: A clinical practice guideline from the American College of Physicians. Qaseem A et al. Ann Intern Med 2011 Nov 1; 155:625. Free full-text article PDF | PubMed ® abstract]
[Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Vandvik PO. Chest 2012 Feb; 141[2 Suppl]:e637S. Chest article abstract]

Patients’ Online Access to Medical Records
[Inviting patients to read their doctors’ notes: A quasi-experimental study and a look ahead. Delbanco T et al. Ann Intern Med 2012 Oct 2; 157:461. Free full-text article PDF | PubMed ® abstract]
[Association of online patient access to clinicians and medical records with use of clinical services. Palen TE et al. JAMA 2012 Nov 21; 308:2012. PubMed ® abstract]
[Personal health records and health care utilization. Bates DW and Wells S. JAMA 2012 Nov 21; 308:2034. JAMA Editorial preview]

€” Allan S. Brett, MD, Editor-in-Chief, and the JW General Medicine Associate Editors

Published in Journal Watch General Medicine December 27, 2012

Copyright © 2012. Massachusetts Medical Society. All rights reserved.

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